The department of pathology at the Icahn School of Medicine at Mount Sinai has just established the Center for Computational and Systems Pathology, with the goal of using advanced computer science, mathematical techniques, cutting-edge microscope technology and AI to revolutionize pathology practice. This new facility will explore efforts to more accurately classify diseases and guide treatment with computer vision and machine learning techniques. It will also serve as a hub for the development of new tests, partnering with Mount Sinai-based “Precise Medical Diagnostics” (Precise MD).
The new center will be overseen by Carlos Cordon-Cardo, MD PhD, and will be continuing his role as chair of the department of pathology at the Mount Sinai Health System and professor at the Icahn School of Medicine. Associate professor Gerardo Fernandez, MD will be the medical director, working closely with pathology research professor Michael Donovan, MD PhD and Jack Zeineh, MD, director of technology for Precise MD. Precise MD is developing new approaches to characterizing an individual’s cancer through combining multiple data sources and then using mathematical algorithms to analyze them, offering a more sophisticated alternative to standard approaches.
In its initial phase this summer, Precise MD will complete a test used for patients who have had prostatectomies at Mount Sinai Health System to determine which of them are more likely to have a recurrence of cancer and may need additional therapy. The approach will give researchers an in-depth knowledge about the biological behavior about prostate cancer, which will allow them to choose the appropriate patients for active surveillance. A second test will follow next year, which will be used to characterize prostate cancer in newly-diagnosed patients, by which time all prostate cancer patients at Mount Sinai will have the chance to receive this test.
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